Am I Eligible for TRIKAFTA®?

People with CF pictured
may or may not be
taking TRIKAFTA.

TRIKAFTA is for people age 12 years and older with at least one F508del mutation or at least one other mutation in the cystic fibrosis (CF) gene that is responsive to TRIKAFTA. Enter your mutations to see if at least one of them is eligible. You can also use the chart below to determine if you are eligible for TRIKAFTA.

Age:

12 years or older
Trikafta Eligibility

See if the CF gene mutation you entered is correct and search again.

Learn how to enter 2 or more mutations.

If you don’t know your CF gene mutations, it’s important to work with your healthcare provider to identify them. Knowing your mutations can help determine if TRIKAFTA could be right for you.

Based on the information entered, you may be eligible for TRIKAFTA.

Talk with your healthcare provider to see if TRIKAFTA is right for you.

Here is some information about TRIKAFTA that may be helpful:
See the study results
Learn about potential side effects
See how TRIKAFTA works
Watch TRIKAFTA stories

Neither CF gene mutation you entered is eligible for TRIKAFTA.

Talk with your healthcare provider to discuss your CF care plan and treatment options that may be right for you.

See Which Mutations TRIKAFTA Is Indicated For

TRIKAFTA is for the treatment of CF in people age 12 years and older who have at least one copy of the F508del mutation or one of the following CF gene mutations.* If you don't see your mutation in this chart, try using the tool above or talk to your healthcare provider.

3

  • 3141del9

5

  • 546insCTA

A

  • A1067T
  • A455E
  • A46D
  • A349V
  • A1006E
  • A120T
  • A234D
  • A554E

D

  • D110E
  • D110H
  • D1152H
  • D1270N
  • D579G
  • D443Y
  • D924N
  • D192G
  • D979V
  • D614G
  • D836Y
  • D443Y;G576A;R668C

E

  • E193K
  • E56K
  • E474K
  • E116K
  • E60K
  • E588V
  • E92K
  • E403D
  • E822K

F

  • F508del
  • F1052V
  • F1074L
  • F311L
  • F575Y
  • F1099L
  • F508C
  • F311del
  • F191V
  • F1016S
  • F508C;S1251N

G

  • G1069R
  • G1244E
  • G1349D
  • G178R
  • G551D
  • G551S
  • G85E
  • G1061R
  • G480C
  • G27R
  • G463V
  • G628R
  • G622D
  • G126D
  • G970D
  • G194R
  • G314E
  • G194V
  • G576A
  • G1249R
  • G178E
  • G576A;R668C

H

  • H139R
  • H1085R
  • H1085P
  • H939R
  • H1375P
  • H1054D
  • H199Y

I

  • I502T
  • I618T
  • I175V
  • I1366N
  • I601F
  • I980K
  • I1269N
  • I1027T
  • I148T
  • I336K
  • I807M
  • I1139V

K

  • K1060T

L

  • L206W
  • L1077P
  • L165S
  • L1335P
  • L967S
  • L320V
  • L346P
  • L1324P
  • L997F
  • L15P
  • L453S
  • L1480P

M

  • M1101K
  • M265R
  • M152V
  • M952I
  • M952T

P

  • P67L
  • P5L
  • P205S
  • P574H

Q

  • Q98R
  • Q1291R
  • Q237E
  • Q237H
  • Q359R

R

  • R1070Q
  • R1070W
  • R117C
  • R117H
  • R347H
  • R352Q
  • R74W
  • R347P
  • R117G
  • R170H
  • R334L
  • R117L
  • R31L
  • R933G
  • R352W
  • R117P
  • R258G
  • R751L
  • R347L
  • R1283S
  • R1162L
  • R553Q
  • R792G
  • R1066H
  • R668C
  • R334Q
  • R1283M
  • R75Q
  • R74Q
  • R74W;V201M;D1270N
  • R74W;D1270N
  • R74W;V201M

S

  • S1251N
  • S1255P
  • S549N
  • S549R
  • S945L
  • S977F
  • S13F
  • S1159F
  • S912L
  • S1159P
  • S589N
  • S341P
  • S492F
  • S737F
  • S364P

T

  • T1053I
  • T1036N
  • T338I

V

  • V456A
  • V456F
  • V201M
  • V562I
  • V1153E
  • V1240G
  • V1293G
  • V754M
  • V232D

W

  • W361R
  • W1098C
  • W1282R

Y

  • Y563N
  • Y161D
  • Y109N
  • Y1014C
  • Y161S
  • Y1032C

*Predicted to respond to TRIKAFTA based on results in a laboratory setting. Not clinically evaluated.

Keep Learning About TRIKAFTA
Learn about potential side effects
See the study results
Keep Learning About TRIKAFTA
Learn about potential side effects
See the study results