TRIKAFTA is a breakthrough treatment for people with CF age 12
years and older with at least one copy of the F508del mutation or
at least one other responsive mutation.


CF will always be part of the equation, but you know there's more
to who you are.

Make TRIKAFTA part of your equation—a triple combination
therapy that treats the underlying cause.

TRIKAFTA is a breakthrough
treatment for people with CF age
12 years and older with at least
one copy of the F508del mutation
or at least one other responsive mutation.


CF will always be part of the equation,
but you know there's more
to who you are.

Make TRIKAFTA part of your equation—a triple combination
therapy that treats the underlying cause.

More people are now eligible.
Megan, age 20
F508del/621+1G→T

People with CF pictured may or may not be taking TRIKAFTA.

How TRIKAFTA™ works

More than 11,000 people have initiated TRIKAFTA.

Based on prescriptions shipped from specialty pharmacies in the US as of May 2020 for patients 12 years and older. Data does not include all patients, patients' CF gene mutations, and patients who have stopped treatment.

Hear from 3 patients who have initiated TRIKAFTA.

Check Your Eligibility

TRIKAFTA is for people age 12 years and older with at least one F508del mutation or at least one other mutation in the CF gene that is responsive to TRIKAFTA. Enter your mutations to see if at least one of them is eligible.

Age:

12 years or older
Trikafta Eligibility

See if the CF gene mutation you entered is correct and search again. 
You can view the list of eligible TRIKAFTA mutations here.

Learn how to enter 2 or more mutations.

If you don’t know your CF gene mutations, it’s important to work with your healthcare provider to identify them. Knowing your mutations can help determine if TRIKAFTA could be right for you.

You can view the list of eligible mutations here.

Based on the information entered, you may be eligible for TRIKAFTA.

Talk with your healthcare provider to see if TRIKAFTA is right for you.

Here is some information about TRIKAFTA that may be helpful:

Neither CF gene mutation you entered is eligible for TRIKAFTA.

Talk with your healthcare provider to discuss your CF care plan and treatment options that may be right for you.

You can view the list of eligible mutations here.

The TRIKAFTA Brochure
The TRIKAFTA Brochure

Get answers to common questions, such as:

  • How does TRIKAFTA work?

  • What are the study details and results?

  • What are the possible side effects?

Get to Know Vertex GPS™:!break Guidance & Patient Support

Vertex GPS offers eligible patients ongoing one-on-one support, right from the start of treatment. Patient Support Specialists can help you navigate questions about insurance, reimbursement, and potential co-pay assistance. You can even get tips for your Vertex treatment and resources that may help you stay on track. No matter where you’re headed, Vertex GPS is with you along the way.