Clayton, age 5
F508del/G542X
Dale, Clayton’s dad
Clayton, age 5
F508del/G542X
Dale, Clayton’s dad
Clayton, age 5
F508del/G542X
Dale, Clayton’s dad
People with CF pictured have taken TRIKAFTA and
were compensated for their participation.
People with CF pictured have taken TRIKAFTA and were compensated for their participation.
Regular testing helps your healthcare provider proactively monitor your liver function.
Your
Your
Your
liver function testing schedule
liver function testing schedule
liver function testing schedule
This schedule* is recommended for anyone starting a triple combination CFTR modulator, including TRIKAFTA®. Tests will be more frequent at first, then less frequent over time.
*Your healthcare provider may test more often if, for example, you have had liver problems before or high levels of liver enzymes.
*Your healthcare provider may test more often if, for example, you have had liver problems before or high levels of liver enzymes.
*Your healthcare provider may test more often if, for example, you have had liver problems before or high levels of liver enzymes.
Scheduling tip: Ask if you could have a blood test at your next regular CF center visit or healthcare provider appointment.
Get the TRIKAFTA liver monitoring fact sheet
Learn why liver function tests are important, where you can get tested, and how you can start planning for your tests.
Learn why liver function tests are important, where you can get tested, and how you can start planning for your tests.
Learn why liver function tests are important, where you can get tested, and how you can start planning for your tests.


TESTING TIPS FOR KIDS
TESTING TIPS FOR KIDS
TESTING TIPS FOR KIDS
Taking your loved one for a blood test isn't always easy, but a little preparation can go a long way. These tips may help you both have a better experience.
Taking your loved one for a blood test isn't always easy, but a little preparation can go a long way. These tips may help you both have a better experience.
Taking your loved one for a blood test isn't always easy, but a little preparation can go a long way. These tips may help you both have a better experience.

Hydrate
Drinking extra water the day before or morning of the test can make a blood draw easier.

Distract
Bringing a favorite book or toy can help distract your loved one before and during the test.

Reward
Planning a treat or activity for after the test can boost your loved one’s mood and encourage cooperation.

Pretend
Knowing what to expect really helps. Give a blood test to a stuffed animal to show your loved one what happens.

Sing
Music could be comforting. Sing along to your favorite songs or try this catchy tune.

Plan
Hungry or tired kids rarely stay calm. Pick a time when they’re well rested and fed.
Christian, age 16
F508del/2307insA
Christian, age 16
F508del/2307insA
Christian, age 16
F508del/2307insA
Staying on track
with TRIKAFTA
with TRIKAFTA
with TRIKAFTA
What is TRIKAFTA® (elexacaftor/tezacaftor/
ivacaftor and ivacaftor)?TRIKAFTA is a prescription medicine used for the treatment of cystic fibrosis (CF) in people aged 2 years and older who have at least one copy of the F508del mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene or another mutation that is responsive to treatment with TRIKAFTA.
Talk to your healthcare provider to learn if you have an indicated CF gene mutation.
It is not known if TRIKAFTA is safe and effective in children under 2 years of age.
IMPORTANT SAFETY INFORMATION
What is the most important information I should know about TRIKAFTA?
TRIKAFTA can cause serious liver damage and liver failure. Liver failure leading to transplantation and death has been seen in some people with or without a history of liver problems taking TRIKAFTA.
Your healthcare provider will do blood tests to check your liver:
- before you start TRIKAFTA
- then every month during your first 6 months of taking TRIKAFTA
- then every 3 months during the next 12 months of taking TRIKAFTA
- then at least every year while you are taking TRIKAFTA
What is TRIKAFTA® (elexacaftor/tezacaftor/
ivacaftor and ivacaftor)?TRIKAFTA is a prescription medicine used for the treatment of cystic fibrosis (CF) in people aged 2 years and older who have at least one copy of the F508del mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene or another mutation that is responsive to treatment with TRIKAFTA.
Talk to your healthcare provider to learn if you have an indicated CF gene mutation.
It is not known if TRIKAFTA is safe and effective in children under 2 years of age.
IMPORTANT SAFETY INFORMATION
What is the most important information I should know about TRIKAFTA?
TRIKAFTA can cause serious liver damage and liver failure. Liver failure leading to transplantation and death has been seen in some people with or without a history of liver problems taking TRIKAFTA.
Your healthcare provider will do blood tests to check your liver:
- before you start TRIKAFTA
- then every month during your first 6 months of taking TRIKAFTA
- then every 3 months during the next 12 months of taking TRIKAFTA
- then at least every year while you are taking TRIKAFTA